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Faculté des Sciences appliquées
Faculté des Sciences appliquées
MASTER THESIS
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Numerical Simulation of the Aggregation and Spreading of the Tau Protein in the Brain

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Hortelan, Valentine ULiège
Promotor(s) : Phillips, Christophe ULiège
Date of defense : 25-Jun-2018/26-Jun-2018 • Permalink : http://hdl.handle.net/2268.2/4517
Details
Title : Numerical Simulation of the Aggregation and Spreading of the Tau Protein in the Brain
Translated title : [fr] Simulation numérique de l’agrégation et de la répartition des protéines tau dans le cerveau
Author : Hortelan, Valentine ULiège
Date of defense  : 25-Jun-2018/26-Jun-2018
Advisor(s) : Phillips, Christophe ULiège
Committee's member(s) : Benali, Habib 
Drion, Guillaume ULiège
Maquet, Pierre ULiège
Language : English
Number of pages : 50-100
Keywords : [en] Alzheimer's disease, tau protein, mathematical modeling, numerical simulation
Discipline(s) : Engineering, computing & technology > Multidisciplinary, general & others
Research unit : Perform Center
Name of the research project : Numerical simulation of the aggregation and spreading of the tau protein in the brain
Institution(s) : Université de Liège, Liège, Belgique
Université de Concordia, Montréal, Canada
Degree: Master en ingénieur civil biomédical, à finalité spécialisée
Faculty: Master thesis of the Faculté des Sciences appliquées

Abstract

[en] This project takes place in the field of research of Alzheimer's disease. One of the two major hallmarks of the dementia is the tau protein pathological aggregation and spreading in the brain. The present work aims at providing to the scientific community an in silico tool that would improve the understanding of these processes, by simulating their evolution over time, at the subject's level.


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Author

  • Hortelan, Valentine ULiège Université de Liège > Master ing. civ. biomed., à fin.

Promotor(s)

Committee's member(s)

  • Benali, Habib Concordia University - PERFORM Center > Engineering, Computer Science
  • Drion, Guillaume ULiège Université de Liège - ULiège > Dép. d'électric., électron. et informat. (Inst.Montefiore) > Systèmes et modélisation
    ORBi View his publications on ORBi
  • Maquet, Pierre ULiège Université de Liège - ULiège > Département des sciences cliniques > Neurologie
    ORBi View his publications on ORBi
  • Total number of views 109
  • Total number of downloads 1227










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