Faculté des Sciences appliquées
Faculté des Sciences appliquées

Development of a new manufacturing process and control methods for intraocular lenses from innovative biomaterials

Lohest, Justine ULiège
Promotor(s) : Lambert, Stéphanie ULiège
Date of defense : 22-Jan-2021 • Permalink :
Title : Development of a new manufacturing process and control methods for intraocular lenses from innovative biomaterials
Translated title : [fr] Développement d'un nouveau procédé de fabrication et des méthodes de contrôle pour lentilles intraoculaires à partir de biomatériaux innovants
Author : Lohest, Justine ULiège
Date of defense  : 22-Jan-2021
Advisor(s) : Lambert, Stéphanie ULiège
Committee's member(s) : Keck-Antoine, Klaus ULiège
Jérôme, Christine ULiège
Willet, Nicolas 
Language : English
Number of pages : 99
Discipline(s) : Engineering, computing & technology > Chemical engineering
Institution(s) : Université de Liège, Liège, Belgique
Degree: Master en ingénieur civil en chimie et science des matériaux, à finalité spécialisée
Faculty: Master thesis of the Faculté des Sciences appliquées


[en] Cataract surgery is the most frequently performed ophthalmologic surgery in the world. It consists in replacing the opaque crystalline lens with an intraocular implant. A large number of implants is available to meet the different expectations of patients. These lenses differ by the material used in their synthesis, their design and the optical performance brought to the patients.

PhysIOL is a company specialised in the production of intraocular lenses. In order to increase its production capacity, the company has developed the Sun project. The aim of this project is to develop a new process for manufacturing lenses by semi-moulding. This technique consists in moulding one side of the lens and machining the second one. This new semi-moulding process only concerns the production of hydrophobic intraocular lenses.

This master thesis focuses entirely on this new production process. The objective is to determine whether there are steps in the semi-moulding process that can be improved. Tests, called chemical tests, were performed to study the impact of different parameters on the properties of the polymer and to determine which validation tests are capable of identifying these impacts. Then, so-called mechanical tests were carried out. They focus on the cap removal stage and aim to reduce the rate of rejects. Finally, tests were carried out to remove the polymerised material from the mould. Influences of temperature, immersion in isopropanol and in an ultrasonic bath were studied.



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  • Lohest, Justine ULiège Université de Liège > Master ingé. civil chim. & sc. mat., à fin.


Committee's member(s)

  • Keck-Antoine, Klaus ULiège Université de Liège - ULiège > Department of Chemical Engineering > Procédés industriels de polymérisation
    ORBi View his publications on ORBi
  • Jérôme, Christine ULiège Université de Liège - ULiège > Département de chimie (sciences) > Centre d'études et de rech. sur les macromolécules (CERM)
    ORBi View his publications on ORBi
  • Willet, Nicolas Physiol
  • Total number of views 43
  • Total number of downloads 0

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