INSULIN SENSITIVITY TESTING : MODEL-BASED SUBCUTANEOUS-ORAL INSULIN SENSITIVITY TESTING

Abstract

Insulin sensitivity tests are either low resolution like the oral glucose tolerance test, or costly and invasive, like the DISST and FSIVGTT. The goal of this work is to translate the DISST model-based test to a far less invasive version that will eventually utilise oral glucose delivery and non-invasive needle-free blood test sampling. This work is part of the overall NZ National Challenge 7 SfTI. It will include modelling analysis and development of the test using the validated models and virtual patients, culminating in limited clinical testings to prove the concept.