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Nanobodies® for the detection and quantification of proteins associated with Neutrophil Extracellular Traps

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Dumont, Teo ULiège
Promotor(s) : Dumoulin, Mireille ULiège
Date of defense : 4-Sep-2024 • Permalink : http://hdl.handle.net/2268.2/21102
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Title : Nanobodies® for the detection and quantification of proteins associated with Neutrophil Extracellular Traps
Translated title : [fr] Nanobodies® pour la détection et la quantification des protéines associées aux Neutrophil Extracellular Traps
Author : Dumont, Teo ULiège
Date of defense  : 4-Sep-2024
Advisor(s) : Dumoulin, Mireille ULiège
Committee's member(s) : Galleni, Moreno ULiège
Lassaux, Patricia ULiège
Kerff, Frédéric ULiège
Language : English
Number of pages : 59
Keywords : [en] Nanobodies
[en] Neutrophil extracellular traps
[en] Quantification
Discipline(s) : Life sciences > Biochemistry, biophysics & molecular biology
Funders : Robotein
Research unit : CIP
Target public : Researchers
Professionals of domain
Institution(s) : Université de Liège, Liège, Belgique
Degree: Master en biochimie et biologie moléculaire et cellulaire, à finalité approfondie
Faculty: Master thesis of the Faculté des Sciences

Abstract

[en] Neutrophil extracellular traps (NETs) represent one of the defense mechanisms employed by neutrophils during the immune response. The excessive formation of NETs is associated with various diseases, such as inflammatory lung diseases, cardiovascular diseases, neurodegenerative, or autoimmune disorders. NETs are decorated with various enzymes that also contribute to the diseases. The aim of this study was to optimize the detection and quantification of of this enzyme using Nanobodies®.


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  • Dumont, Teo ULiège Université de Liège > Master bioch. & biol. mol. , fin. approf.

Promotor(s)

Committee's member(s)

  • Galleni, Moreno ULiège Université de Liège - ULiège > Département des sciences de la vie > Macromolécules biologiques
    ORBi View his publications on ORBi
  • Lassaux, Patricia ULiège Université de Liège - ULiège > Département des sciences biomédicales et précliniques > Département des sciences biomédicales et précliniques
    ORBi View his publications on ORBi
  • Kerff, Frédéric ULiège Université de Liège - ULiège > Département des sciences de la vie > Centre d'Ingénierie des Protéines (CIP)
    ORBi View his publications on ORBi
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