Master Thesis Online
Thesis, COLLÉGIALITÉ
Schmitz, Louisa 
Promotor(s) :
Neirinckx, Virginie
Date of defense : 5-Jul-2022 • Permalink : http://hdl.handle.net/2268.2/14857
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Louisa_Schmitz-Master-thesis-2022.pdfDetails
| Title : | Thesis, COLLÉGIALITÉ |
| Author : | Schmitz, Louisa
|
| Date of defense : | 5-Jul-2022 |
| Advisor(s) : | Neirinckx, Virginie
|
| Committee's member(s) : | Close, Pierre
Scholtes, Félix
Dupont, Laura
|
| Language : | English |
| Number of pages : | 62 |
| Keywords : | [en] Gliomas [en] PTPRZ1 [en] Pediatric |
| Discipline(s) : | Human health sciences > Neurology |
| Institution(s) : | Université de Liège, Liège, Belgique |
| Degree: | Master en sciences biomédicales, à finalité approfondie |
| Faculty: | Master thesis of the Faculté de Médecine |
Abstract
[en] Malignant gliomas are aggressive glial cancers of central nervous system. Therapies exist such as surgery, radiotherapy and chemotherapy but resistance to therapies and recurrence decrease the survival rate. Protein tyrosine phosphatase receptor type Zeta1 (PTPRZ1) could be a potential target for adult and pediatric gliomas therapies. The objective of this thesis is to validate the presence of PTPRZ1 on adult and pediatric cell cultures, as well as to understand the function of the receptor in vitro.
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